A mild copper-catalyzed aerobic oxidative thiocyanation of arylboronic acids with TMSNCS.
نویسندگان
چکیده
A facile and efficient transformation of arylboronic acids to their corresponding aryl thiocyanates has been successfully developed. Based on the CuCl-catalyzed oxidative cross-coupling reaction between arylboronic acids and trimethylsilylisothiocyanate (TMSNCS) under oxygen atmosphere, the transformation can be readily conducted at ambient temperature. The newly-developed protocol provided a competitive synthetic approach to aryl thiocyanates that can tolerate a broad range of reactive functional groups and/or strong electron-withdrawing groups.
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ورودعنوان ژورنال:
- Organic & biomolecular chemistry
دوره 13 3 شماره
صفحات -
تاریخ انتشار 2015